“Given the potential for gene drives to alter entire wild populations and therefore ecosystems, the development of this technology must include robust safeguards and methods of control (Oye et al., 2014). Whereas existing gene drive proposals focus on adding genes (Ito et al., 2002), disrupting existing genes (Burt, 2003), or suppressing populations, RNA-guided gene drives will also be capable of replacing existing sequences with altered versions that have been recoded to remove the sites targeted by the drive”

http://elifesciences.org/content/3/e03401.full

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RNA guided gene drives